From which type of tissue do sarcomas originate?

Sarcomas are a group of cancers that arise from mesenchymal tissues, which include connective tissues such as bone, cartilage, fat, and blood vessels. Because these tumors originate from connective tissue, they are classified as sarcomas. This differentiates them from carcinomas, which originate from epithelial tissue.

While muscle tissue, a subtype of connective tissue, is related to some forms of sarcomas, such as rhabdomyosarcoma (which arises from skeletal muscle), the broader category encompasses a variety of connective tissues. Thus, the foundational origin of all sarcomas is indeed from connective tissue, making the connection clear and explaining why this choice is the most accurate.